Differential requirement for protein synthesis in presynaptic unmuting and muting in hippocampal glutamate terminals.
Synaptic function and plasticity are crucial for information processing within the nervous system.In glutamatergic hippocampal neurons, presynaptic function is silenced, or Home muted, after strong or prolonged depolarization.This muting is neuroprotective, but the underlying mechanisms responsible for muting and its reversal, unmuting, remain to b